Abstract: Since the advent of COVID-19 mRNA vaccines, mRNA has become one of the most promising nucleic acid therapeutics. However, a major challenge now is how to deliver mRNA to targeting cells effectively and increase mRNA expression yield but de-risk
Resumen: Since the advent of COVID-19 mRNA vaccines, mRNA has become one of the most promising nucleic acid therapeutics. However, a major challenge now is how to deliver mRNA to targeting cells effectively and increase mRNA expression yield but de-risk
Resumen: Biodegradable magnesium (Mg) alloys represent a promising class of materials for next-generation biomedical implants, particularly endoluminal devices. Their major limitation, however, lies in the difficulty of controlling corrosion in the aggressive physiological environment, where chloride-rich solutions promote rapid dissolution
Resumen: «Additive manufacturing processes are predominantly governed by complex thermomechanical interactions that critically influence the mechanical properties and the quality of the final product. This study first developed a mathematical framework of general small-strain thermo-mechanics that can incorporate an arbitrary
Resumen In this talk, José Luis Plaza will briefly discuss the development of Crystal Semiconductor Technologies company, born at the Crystal Growth Laboratory of the Autonomous University of Madrid (LCC-UAM). He will introduce how the knowledge gained from more than
Resumen: Beyond its capability to create intricate geometries, Laser Powder Bed Fusion (L-PBF) is a powerful tool for tailoring the microstructure of metallic materials. By carefully adjusting process parameters, L-PBF enables fine tuning of crystallographic textures – a particularly critical
Resumen: El seminario explorará los principales desafíos en el diseño y desarrollo de sistemas de administración de fármacos dirigidos a tratamientos específicos de enfermedades. Se hará especial énfasis en estrategias para superar barreras biológicas, con un enfoque en la entrega
Resumen: The talk will explore the key challenges in the design and development of drug delivery systems aimed at targeted disease treatment. Special emphasis will be placed on strategies for crossing biological barriers, with a focus on targeting the brain,
Resumen: Sports injuries often arise from the limited ability of the human locomotor system to effectively store and release elastic energy during high-demand activities (Nigg & Wakeling, 2001). Current athletic footwear technologies rely heavily on energy-absorbing polymers that reduce impact
Resumen: The development of new and novel materials is critical for driving innovations in the next generation of devices and systems for applications in nanoelectronics, energy conversion and storage, and quantum computing. As the limitations of silicon-based technologies become increasingly
Resumen: Additive manufacturing (AM), particularly laser powder bed fusion (LPBF), has revolutionized the fabrication of high-performance metal components for aerospace by enabling more complex geometries to be produced with superior mechanical properties and minimal material waste [1-5]. High-strength Ni-based superalloys
La defensa de la tesis doctoral se llevará a cabo en Sala 3.S01.08, Edificio Biblioteca Rey Pastor, Universidad Carlos III – Campus de Leganés. Ha sido asesorada por Directora: Dra. María Teresa Pérez Prado y Tutora: Prof. Mónica Campos Gómez.
Resumen: The presence of minor grain boundary solutes such as boron and zirconium can have significant consequences for the production of superalloys using additive manufacturing methods. On the one hand, their presence in the bulk chemistry is crucial for achieving
Resumen: Optimizing the performance of engineering alloys during manufacturing and service conditions requires a keen understanding of their microstructure evolution under applied temperature and load. It is thus a challenging task, because under the influence of an external load and/or
Resumen: Ultraviolet (UV) radiation is efficiently absorbed by the atmosphere of the Earth and its relevance and usefulness in materials processing has been often disregarded being this type of studies relegated to astrophysics and space science and exploration. In this
Resumen: Additive manufacturing (AM) is revolutionizing how we synthesize, produce, and use metallic materials. However, out of hundreds of commercially available engineering alloys, only a handful are readily printable. This arises from the extreme heating and cooling rates associated with
La defensa de la tesis doctoral se llevará a cabo en la Sala Leonardo Torres Quevedo, Escuela Técnica Superior de Ingenieros de Caminos, Canales y Puertos (UPM). La disertación se titula «Desarrollo de andamiajes biodegradables impresos en 3D para ingeniería
Resumen: This thesis investigates key challenges in the development of next-generation lithium-ion batteries by using a fully silicon-based nanowire anode as a model system. The work focuses on understanding the mechanisms responsible for capacity fading—such as SEI instability, mechanical degradation,